Publications

Tan, Z., Q. Liu, R. Jiang, L. Lv, S. S. Shoto, I. Maillet, V. Quesniaux, J. Tang, W. Zhang, B. Sun, and B. Ryffel. 2018.

Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells. Cell Mol Immunol

Stanek, K. A., and C. Mura. 2018.

Producing Hfq/Sm Proteins and sRNAs for Structural and Biophysical Studies of Ribonucleoprotein Assembly. Methods Mol Biol

Secher, T., I. Maillet, C. Mackowiak, J. Le Bérichel, A. Philippeau, C. Panek, M. Boury, E. Oswald, A. Saoudi, F. Erard, M. Le Bert, V. Quesniaux, A. Couturier-Maillard, and B. Ryffel. 2018.

The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice. Sci Rep

Perche, O., C. Felgerolle, M. Ardourel, A. Bazinet, A. Pâris, R. Rossignol, G. Meyer-Dilhet, A. L. Mausset-Bonnefont, B. Hébert, D. Laurenceau, C. Montécot-Dubourg, A. Menuet, J. C. Bizot, J. Pichon, I. Ranchon-Cole, and S. Briault. 2018.

Early Retinal Defects in Fmr1(-/y) Mice: Toward a Critical Role of Visual Dys-Sensitivity in the Fragile X Syndrome Phenotype? Frontiers in cellular neuroscience

Palomo, J., V. F. J. Quesniaux, D. Togbe, F. Reverchon, and B. Ryffel. 2018.

Unravelling the roles of innate lymphoid cells in cerebral malaria pathogenesis. Parasite Immunol

Michaudel, C., I. Maillet, L. Fauconnier, V. Quesniaux, K. F. Chung, C. Wiegman, D. Peter, and B. Ryffel. 2018.

Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation. Front Immunol

Michaudel, C., C. Mackowiak, I. Maillet, L. Fauconnier, C. A. Akdis, M. Sokolowska, A. Dreher, H. T. Tan, V. F. Quesniaux, B. Ryffel, and D. Togbe. 2018.

Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL-33. J Allergy Clin Immunol

Michaudel, C., L. Fauconnier, Y. Julé, and B. Ryffel. 2018.

Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice. Sci Rep

Marinho, F. V., S. Benmerzoug, S. Rose, P. C. Campos, J. T. Marques, A. Báfica, G. Barber, B. Ryffel, S. C. Oliveira, and V. F. J. Quesniaux. 2018.

The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection. J Innate Immun

Feat-Vetel, J., V. Larrigaldie, G. Meyer-Dilhet, A. Herzine, C. Mougin, A. Laugeray, T. Gefflaut, O. Richard, V. Quesniaux, C. Montécot-Dubourg, and S. Mortaud. 2018.

Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology

Fanny, M., M. Nascimento, L. Baron, C. Schricke, I. Maillet, M. Akbal, N. Riteau, M. Le Bert, V. Quesniaux, B. Ryffel, A. Gombault, S. Même, W. Même, and I. Couillin. 2018.

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Front Immunol

Di Padova, F., V. F. J. Quesniaux, and B. Ryffel. 2018.

MyD88 as a therapeutic target for inflammatory lung diseases. Expert Opin Ther Targets

Couturier-Maillard, A., N. Froux, J. Piotet-Morin, C. Michaudel, L. Brault, J. Le Bérichel, A. Sénéchal, P. Robinet, P. Chenuet, S. Jejou, L. Dumoutier, J. C. Renauld, J. Iovanna, S. Huber, M. Chamaillard, V. Quesniaux, H. Sokol, M. Chamaillard, and B. Ryffel. 2018.

Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation. Mucosal Immunol

Cordero, M. D., M. R. Williams, and B. Ryffel. 2018.

AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging. Trends Endocrinol Metab

Cordero, M. D., E. Alcocer-Gómez, and B. Ryffel. 2018.

Gain of function mutation and inflammasome driven diseases in human and mouse models. J Autoimmun

Benmerzoug, S., S. Rose, B. Bounab, D. Gosset, L. Duneau, P. Chenuet, L. Mollet, M. Le Bert, C. Lambers, S. Geleff, M. Roth, L. Fauconnier, D. Sedda, C. Carvalho, O. Perche, D. Laurenceau, B. Ryffel, L. Apetoh, A. Kiziltunc, H. Uslu, F. S. Albez, M. Akgun, D. Togbe, and V. F. J. Quesniaux. 2018.

STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun

Benmerzoug, S., F. V. Marinho, S. Rose, C. Mackowiak, D. Gosset, D. Sedda, E. Poisson, C. Uyttenhove, J. Van Snick, M. Jacobs, I. Garcia, B. Ryffel, and V. F. J. Quesniaux. 2018.

GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection. Sci Rep

Agoro, R., M. Taleb, V. F. J. Quesniaux, and C. Mura. 2018.

Cell iron status influences macrophage polarization. PLoS One

Stanek, K. A., J. Patterson-West, P. S. Randolph, and C. Mura. 2017.

Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode. Acta crystallographica. Section D, Structural biology

Reverchon, F., S. Mortaud, M. Sivoyon, I. Maillet, A. Laugeray, J. Palomo, C. Montécot, A. Herzine, S. Meme, W. Meme, F. Erard, B. Ryffel, A. Menuet, and V. F. J. Quesniaux. 2017.

IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathog

Marinho, F. V., S. Benmerzoug, S. C. Oliveira, B. Ryffel, and V. F. J. Quesniaux. 2017.

The Emerging Roles of STING in Bacterial Infections. Trends Microbiol

Madouri, F., P. Chenuet, C. Beuraud, L. Fauconnier, T. Marchiol, N. Rouxel, A. Ledru, M. Gallerand, V. Lombardi, L. Mascarell, Q. Marquant, L. Apetoh, F. Erard, M. Le Bert, F. Trovero, V. F. J. Quesniaux, B. Ryffel, and D. Togbe. 2017.

Protein kinase Cθ controls type 2 innate lymphoid cell and T(H)2 responses to house dust mite allergen. J Allergy Clin Immunol

Li, C., I. Maillet, C. Mackowiak, C. Viala, F. Di Padova, M. Li, D. Togbe, V. Quesniaux, Y. Lai, and B. Ryffel. 2017.

Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells. Cell Death Dis

Laugeray, A., A. Herzine, O. Perche, O. Richard, C. Montecot-Dubourg, A. Menuet, S. Mazaud-Guittot, L. Lesné, B. Jegou, and S. Mortaud. 2017.

In utero and lactational exposure to low-doses of the pyrethroid insecticide cypermethrin leads to neurodevelopmental defects in male mice-An ethological and transcriptomic study. PLoS One

Chenuet, P., L. Fauconnier, F. Madouri, T. Marchiol, N. Rouxel, A. Ledru, P. Mauny, R. Lory, C. Uttenhove, J. van Snick, Y. Iwakura, F. di Padova, V. Quesniaux, D. Togbe, and B. Ryffel. 2017.

Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice. Clin Sci (Lond)

Benmerzoug, S., and V. F. J. Quesniaux. 2017.

Bioengineered 3D Models for Studying Human Cell-Tuberculosis Interactions. Trends Microbiol

Agoro, R., S. Benmerzoug, S. Rose, M. Bouyer, R. Gozzelino, I. Garcia, B. Ryffel, V. F. J. Quesniaux, and C. Mura. 2017.

An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates With Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection. J Infect Dis

Segueni, N., E. Tritto, M. L. Bourigault, S. Rose, F. Erard, M. Le Bert, M. Jacobs, F. Di Padova, D. P. Stiehl, P. Moulin, D. Brees, S. D. Chibout, B. Ryffel, M. Kammüller, and V. F. Quesniaux. 2016.

Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization. Sci Rep

Segueni, N., S. Benmerzoug, S. Rose, A. Gauthier, M. L. Bourigault, F. Reverchon, A. Philippeau, F. Erard, M. Le Bert, H. Bouscayrol, T. Wachter, I. Garcia, G. Kollias, M. Jacobs, B. Ryffel, and V. F. Quesniaux. 2016.

Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection. Sci Rep

Riteau, N., A. Gombault, and I. Couillin. 2016.

Assessment of Inflammasome Activation by Cytokine and Danger Signal Detection. Methods Mol Biol

Michaudel, C., A. Couturier-Maillard, P. Chenuet, I. Maillet, C. Mura, I. Couillin, A. Gombault, V. F. Quesniaux, F. Huaux, and B. Ryffel. 2016.

Inflammasome, IL-1 and inflammation in ozone-induced lung injury. Am J Clin Exp Immunol

McAnany, C. E., and C. Mura. 2016.

Claws, Disorder, and Conformational Dynamics of the C-Terminal Region of Human Desmoplakin. The journal of physical chemistry. B

Laudier, B., T. Epiais, A. Pâris, A. Menuet, S. Briault, C. Ozsancak, and O. Perche. 2016.

Molecular and clinical analyses with neuropsychological assessment of a case of del(10)(q26.2qter) without intellectual disability: Genomic and transcriptomic combined approach and review of the literature. American journal of medical genetics. Part A

Herzine, A., A. Laugeray, J. Feat, A. Menuet, V. Quesniaux, O. Richard, J. Pichon, C. Montécot-Dubourg, O. Perche, and S. Mortaud. 2016.

Perinatal Exposure to Glufosinate Ammonium Herbicide Impairs Neurogenesis and Neuroblast Migration through Cytoskeleton Destabilization. Frontiers in cellular neuroscience

Féron, F., B. Gepner, E. Lacassagne, D. Stephan, B. Mesnage, M. P. Blanchard, N. Boulanger, C. Tardif, A. Devèze, S. Rousseau, K. Suzuki, J. C. Izpisua Belmonte, M. Khrestchatisky, E. Nivet, and M. Erard-Garcia. 2016.

Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders. Molecular psychiatry

Ekmekci, B., C. E. McAnany, and C. Mura. 2016.

An Introduction to Programming for Bioscientists: A Python-Based Primer. PLoS computational biology

Agoro, R., and C. Mura. 2016.

Inflammation-induced up-regulation of hepcidin and down-regulation of ferroportin transcription are dependent on macrophage polarization. Blood cells, molecules & diseases

Palomo, J., F. Reverchon, J. Piotet, A. G. Besnard, A. Couturier-Maillard, I. Maillet, M. Tefit, F. Erard, D. Mazier, B. Ryffel, and V. F. Quesniaux. 2015.

Critical role of IL-33 receptor ST2 in experimental cerebral malaria development. Eur J Immunol

Madouri, F., N. Guillou, L. Fauconnier, T. Marchiol, N. Rouxel, P. Chenuet, A. Ledru, L. Apetoh, F. Ghiringhelli, M. Chamaillard, S. G. Zheng, F. Trovero, V. F. Quesniaux, B. Ryffel, and D. Togbe. 2015.

Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. J Mol Cell Biol

Gray, C., C. W. Price, C. T. Lee, A. H. Dewald, M. A. Cline, C. E. McAnany, L. Columbus, and C. Mura. 2015.

Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

François, A., A. Gombault, B. Villeret, G. Alsaleh, M. Fanny, P. Gasse, S. M. Adam, B. Crestani, J. Sibilia, P. Schneider, S. Bahram, V. Quesniaux, B. Ryffel, D. Wachsmann, J. E. Gottenberg, and I. Couillin. 2015.

B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis. J Autoimmun

Baron, L., A. Gombault, M. Fanny, B. Villeret, F. Savigny, N. Guillou, C. Panek, M. Le Bert, V. Lagente, F. Rassendren, N. Riteau, and I. Couillin. 2015.

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Cell Death Dis

Wollin, L., I. Maillet, V. Quesniaux, A. Holweg, and B. Ryffel. 2014.

Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J Pharmacol Exp Ther

Rossignol, R., I. Ranchon-Cole, A. Pâris, A. Herzine, A. Perche, D. Laurenceau, P. Bertrand, C. Cercy, J. Pichon, S. Mortaud, S. Briault, A. Menuet, and O. Perche. 2014.

Visual sensorial impairments in neurodevelopmental disorders: evidence for a retinal phenotype in Fragile X Syndrome. PLoS One

Palomo, J., T. Marchiol, J. Piotet, L. Fauconnier, M. Robinet, F. Reverchon, M. Le Bert, D. Togbe, R. Buijs-Offerman, M. Stolarczyk, V. F. Quesniaux, B. J. Scholte, and B. Ryffel. 2014.

Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection. PLoS One

Laugeray, A., A. Herzine, O. Perche, B. Hébert, M. Aguillon-Naury, O. Richard, A. Menuet, S. Mazaud-Guittot, L. Lesné, S. Briault, B. Jegou, J. Pichon, C. Montécot-Dubourg, and S. Mortaud. 2014.

Pre- and postnatal exposure to low dose glufosinate ammonium induces autism-like phenotypes in mice. Frontiers in behavioral neuroscience

Hébert, B., S. Pietropaolo, S. Même, B. Laudier, A. Laugeray, N. Doisne, A. Quartier, S. Lefeuvre, L. Got, D. Cahard, F. Laumonnier, W. E. Crusio, J. Pichon, A. Menuet, O. Perche, and S. Briault. 2014.

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule. Orphanet journal of rare diseases

Guabiraba, R., and B. Ryffel. 2014.

Dengue virus infection: current concepts in immune mechanisms and lessons from murine models. Immunology

Villeret, B., L. Brault, A. Couturier-Maillard, P. Robinet, V. Vasseur, T. Secher, I. Dimier-Poisson, M. Jacobs, S. G. Zheng, V. F. Quesniaux, and B. Ryffel. 2013.

Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice. Am J Clin Exp Immunol

Togbe, D., L. Fauconnier, F. Madouri, T. Marchiol, P. Chenuet, N. Rouxel, A. Ledru, F. Erard, V. Quesniaux, and B. Ryffel. 2013.

Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation. ISRN Allergy

Tan, Z., R. Jiang, X. Wang, Y. Wang, L. Lu, Q. Liu, S. G. Zheng, B. Sun, and B. Ryffel. 2013.

RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. J Mol Cell Biol

Sedhom, M. A., M. Pichery, J. R. Murdoch, B. Foligné, N. Ortega, S. Normand, K. Mertz, D. Sanmugalingam, L. Brault, T. Grandjean, E. Lefrancais, P. G. Fallon, V. Quesniaux, L. Peyrin-Biroulet, G. Cathomas, T. Junt, M. Chamaillard, J. P. Girard, and B. Ryffel. 2013.

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut

Perche, O., A. Menuet, M. Marcos, L. Liu, A. Pâris, K. H. Utami, D. Kervran, V. Cacheux, B. Laudier, and S. Briault. 2013.

Combined deletion of two Condensin II system genes (NCAPG2 and MCPH1) in a case of severe microcephaly and mental deficiency. European journal of medical genetics

Patterson, J., and C. Mura. 2013.

Rapid colorimetric assays to qualitatively distinguish RNA and DNA in biomolecular samples. Journal of visualized experiments : JoVE

Palomo, J., M. Fauconnier, L. Coquard, M. Gilles, S. Meme, F. Szeremeta, L. Fick, J. F. Franetich, M. Jacobs, D. Togbe, J. C. Beloeil, D. Mazier, B. Ryffel, and V. F. Quesniaux. 2013.

Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA. Eur J Immunol

Bourigault, M. L., N. Segueni, S. Rose, N. Court, R. Vacher, V. Vasseur, F. Erard, M. Le Bert, I. Garcia, Y. Iwakura, M. Jacobs, B. Ryffel, and V. F. Quesniaux. 2013.

Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG. Immun Inflamm Dis

Besnard, A. G., S. Struyf, R. Guabiraba, L. Fauconnier, N. Rouxel, P. Proost, C. Uyttenhove, J. Van Snick, I. Couillin, and B. Ryffel. 2013.

CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model. J Leukoc Biol

Riteau, N., L. Baron, B. Villeret, N. Guillou, F. Savigny, B. Ryffel, F. Rassendren, M. Le Bert, A. Gombault, and I. Couillin. 2012.

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death Dis

Perche, O., B. Laudier, A. Menuet, S. Odent, F. Laumonnier, and S. Briault. 2012.

FG syndrome: the FGS2 locus revisited. American journal of medical genetics. Part A

Gombault, A., L. Baron, and I. Couillin. 2012.

ATP release and purinergic signaling in NLRP3 inflammasome activation. Front Immunol

Fauconnier, M., J. Palomo, M. L. Bourigault, S. Meme, F. Szeremeta, J. C. Beloeil, A. Danneels, S. Charron, P. Rihet, B. Ryffel, and V. F. Quesniaux. 2012.

IL-12Rβ2 is essential for the development of experimental cerebral malaria. J Immunol

Besnard, A. G., D. Togbe, I. Couillin, Z. Tan, S. G. Zheng, F. Erard, M. Le Bert, V. Quesniaux, and B. Ryffel. 2012.

Inflammasome-IL-1-Th17 response in allergic lung inflammation. J Mol Cell Biol

Yang, Y., C. Férec, and C. Mura. 2011.

SNP and haplotype analysis reveals new HFE variants associated with iron overload trait. Human mutation

Maillet, I., S. Schnyder-Candrian, I. Couillin, V. F. Quesniaux, F. Erard, R. Moser, S. Fleury, A. Kanda, D. Dombrowicz, D. E. Szymkowski, and B. Ryffel. 2011.

Allergic lung inflammation is mediated by soluble tumor necrosis factor (TNF) and attenuated by dominant-negative TNF biologics. Am J Respir Cell Mol Biol

Gasse, P., N. Riteau, R. Vacher, M. L. Michel, A. Fautrel, F. di Padova, L. Fick, S. Charron, V. Lagente, G. Eberl, M. Le Bert, V. F. Quesniaux, F. Huaux, M. Leite-de-Moraes, B. Ryffel, and I. Couillin. 2011.

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis. PLoS One

Garcia, I., M. L. Olleros, V. F. Quesniaux, M. Jacobs, N. Allie, S. A. Nedospasov, D. E. Szymkowski, and B. Ryffel. 2011.

Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection. Adv Exp Med Biol

Fauconnier, M., M. L. Bourigault, S. Meme, F. Szeremeta, J. Palomo, A. Danneels, S. Charron, L. Fick, M. Jacobs, J. C. Beloeil, B. Ryffel, and V. F. Quesniaux. 2011.

Protein kinase C-theta is required for development of experimental cerebral malaria. Am J Pathol

Court, N., S. Rose, M. L. Bourigault, S. Front, O. R. Martin, J. K. Dowling, E. F. Kenny, L. O’Neill, F. Erard, and V. F. Quesniaux. 2011.

Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms. PLoS One

Cieślik, M., and C. Mura. 2011.

A lightweight, flow-based toolkit for parallel and distributed bioinformatics pipelines. BMC bioinformatics

Cieślik, M., Z. S. Derewenda, and C. Mura. 2011.

Abstractions, algorithms and data structures for structural bioinformatics in PyCogent. Journal of applied crystallography

Besnard, A. G., D. Togbe, N. Guillou, F. Erard, V. Quesniaux, and B. Ryffel. 2011.

IL-33-activated dendritic cells are critical for allergic airway inflammation. Eur J Immunol

Besnard, A. G., R. Sabat, L. Dumoutier, J. C. Renauld, M. Willart, B. Lambrecht, M. M. Teixeira, S. Charron, L. Fick, F. Erard, K. Warszawska, K. Wolk, V. Quesniaux, B. Ryffel, and D. Togbe. 2011.

Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. Am J Respir Crit Care Med

Besnard, A. G., N. Guillou, J. Tschopp, F. Erard, I. Couillin, Y. Iwakura, V. Quesniaux, B. Ryffel, and D. Togbe. 2011.

NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant. Allergy

Soares, A. L., F. R. Coelho, R. Guabiraba, M. Kamal, B. B. Vargaftig, L. Li, J. Li, W. Tavares-de-Lima, and B. Ryffel. 2010.

Tumor necrosis factor is not associated with intestinal ischemia/reperfusion-induced lung inflammation. Shock

Riteau, N., P. Gasse, L. Fauconnier, A. Gombault, M. Couegnat, L. Fick, J. Kanellopoulos, V. F. Quesniaux, S. Marchand-Adam, B. Crestani, B. Ryffel, and I. Couillin. 2010.

Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. Am J Respir Crit Care Med

Quesniaux, V. F., M. Jacobs, N. Allie, S. Grivennikov, S. A. Nedospasov, I. Garcia, M. L. Olleros, Y. Shebzukhov, D. Kuprash, V. Vasseur, S. Rose, N. Court, R. Vacher, and B. Ryffel. 2010.

TNF in host resistance to tuberculosis infection. Curr Dir Autoimmun

Quesniaux, V., F. Erard, and B. Ryffel. 2010.

Adjuvant activity on murine and human macrophages. Methods Mol Biol

Perche, O., F. Laumonnier, L. Baala, M. Y. Ardourel, A. Menuet, V. Robin, S. Mortaud, C. Montécot-Dubourg, O. Richard, J. Pichon, and S. Briault. 2010.

[Autism, genetics and synaptic function alterations]. Pathologie-biologie

Jacolot, S., Y. Yang, P. Paitry, C. Férec, and C. Mura. 2010.

Iron metabolism in macrophages from HFE hemochromatosis patients. Molecular genetics and metabolism

Court, N., V. Vasseur, R. Vacher, C. Frémond, Y. Shebzukhov, V. V. Yeremeev, I. Maillet, S. A. Nedospasov, S. Gordon, P. G. Fallon, H. Suzuki, B. Ryffel, and V. F. Quesniaux. 2010.

Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. J Immunol

Secher, T., V. Vasseur, D. M. Poisson, J. A. Mitchell, F. Q. Cunha, J. C. Alves-Filho, and B. Ryffel. 2009.

Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. J Immunol

Gasse, P., N. Riteau, S. Charron, S. Girre, L. Fick, V. Pétrilli, J. Tschopp, V. Lagente, V. F. Quesniaux, B. Ryffel, and I. Couillin. 2009.

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med

Freitas, A., J. C. Alves-Filho, T. Victoni, T. Secher, H. P. Lemos, F. Sônego, F. Q. Cunha, and B. Ryffel. 2009.

IL-17 receptor signaling is required to control polymicrobial sepsis. J Immunol

Doz, E., S. Rose, N. Court, S. Front, V. Vasseur, S. Charron, M. Gilleron, G. Puzo, I. Fremaux, Y. Delneste, F. Erard, B. Ryffel, O. R. Martin, and V. F. Quesniaux. 2009.

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression. J Biol Chem

Daoud, H., N. Gruchy, J. M. Constans, E. Moussaoui, S. Saumureau, N. Bayou, M. Amy, S. Védrine, P. Y. Vu, A. Rötig, F. Laumonnier, P. Vourc’h, C. R. Andres, N. Leporrier, and S. Briault. 2009.

Haploinsufficiency of the GPD2 gene in a patient with nonsyndromic mental retardation. Human genetics

Daoud, H., F. Bonnet-Brilhault, S. Védrine, M. V. Demattéi, P. Vourc’h, N. Bayou, C. R. Andres, C. Barthélémy, F. Laumonnier, and S. Briault. 2009.

Autism and nonsyndromic mental retardation associated with a de novo mutation in the NLGN4X gene promoter causing an increased expression level. Biological psychiatry

Couillin, I., V. Vasseur, S. Charron, P. Gasse, M. Tavernier, J. Guillet, V. Lagente, L. Fick, M. Jacobs, F. R. Coelho, R. Moser, and B. Ryffel. 2009.

IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. J Immunol

Carlos, D., C. Fremond, A. Samarina, V. Vasseur, I. Maillet, S. G. Ramos, F. Erard, V. Quesniaux, H. Ohtsu, C. L. Silva, L. H. Faccioli, and B. Ryffel. 2009.

Histamine plays an essential regulatory role in lung inflammation and protective immunity in the acute phase of Mycobacterium tuberculosis infection. Infect Immun

Togbe, D., P. L. de Sousa, M. Fauconnier, V. Boissay, L. Fick, S. Scheu, K. Pfeffer, R. Menard, G. E. Grau, B. T. Doan, J. C. Beloeil, L. Renia, A. M. Hansen, H. J. Ball, N. H. Hunt, B. Ryffel, and V. F. Quesniaux. 2008.

Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PLoS One

Jacolot, S., C. Férec, and C. Mura. 2008.

Iron responses in hepatic, intestinal and macrophage/monocyte cell lines under different culture conditions. Blood cells, molecules & diseases

Erard, F., and B. Ryffel. 2008.

Toll like receptor – potential drug targets in infectious disease. Infect Disord Drug Targets

Doz, E., N. Noulin, E. Boichot, I. Guénon, L. Fick, M. Le Bert, V. Lagente, B. Ryffel, B. Schnyder, V. F. Quesniaux, and I. Couillin. 2008.

Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J Immunol

Togbe, D., L. Schofield, G. E. Grau, B. Schnyder, V. Boissay, S. Charron, S. Rose, B. Beutler, V. F. Quesniaux, and B. Ryffel. 2007.

Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol

Jacobs, M., D. Togbe, C. Fremond, A. Samarina, N. Allie, T. Botha, D. Carlos, S. K. Parida, S. Grivennikov, S. Nedospasov, A. Monteiro, M. Le Bert, V. Quesniaux, and B. Ryffel. 2007.

Tumor necrosis factor is critical to control tuberculosis infection. Microbes Infect

Jacobs, M., A. Samarina, S. Grivennikov, T. Botha, N. Allie, C. Fremond, D. Togbe, V. Vasseur, S. Rose, F. Erard, A. Monteiro, V. Quesniaux, and B. Ryffel. 2007.

Reactivation of tuberculosis by tumor necrosis factor neutralization. Eur Cytokine Netw

Gasse, P., C. Mary, I. Guenon, N. Noulin, S. Charron, S. Schnyder-Candrian, B. Schnyder, S. Akira, V. F. Quesniaux, V. Lagente, B. Ryffel, and I. Couillin. 2007.

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest

Fremond, C. M., D. Togbe, E. Doz, S. Rose, V. Vasseur, I. Maillet, M. Jacobs, B. Ryffel, and V. F. Quesniaux. 2007.

IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. J Immunol

Doz, E., S. Rose, J. Nigou, M. Gilleron, G. Puzo, F. Erard, B. Ryffel, and V. F. Quesniaux. 2007.

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan. J Biol Chem

Togbe, D., S. Schnyder-Candrian, B. Schnyder, I. Couillin, I. Maillet, F. Bihl, D. Malo, B. Ryffel, and V. F. Quesniaux. 2006.

TLR4 gene dosage contributes to endotoxin-induced acute respiratory inflammation. J Leukoc Biol

Togbe, D., G. Aurore, N. Noulin, V. F. Quesniaux, S. Schnyder-Candrian, B. Schnyder, V. Vasseur, S. Akira, K. Hoebe, B. Beutler, B. Ryffel, and I. Couillin. 2006.

Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. Lab Invest

Savoy, F., D. M. Nicolle, D. Rivier, C. Chiavaroli, B. Ryffel, and V. F. Quesniaux. 2006.

Synthetic triacylated lipid A derivative activates antigen presenting cells via the TLR4 pathway and promotes antigen-specific responses in vivo. Immunobiology

Ryffel, B., M. Jacobs, S. Parida, T. Botha, D. Togbe, and V. Quesniaux. 2006.

Toll-like receptors and control of mycobacterial infection in mice. Novartis Found Symp

Laumonnier, F., S. Roger, P. Guérin, F. Molinari, R. M’Rad, D. Cahard, A. Belhadj, M. Halayem, A. M. Persico, M. Elia, V. Romano, S. Holbert, C. Andres, H. Chaabouni, L. Colleaux, J. Constant, J. Y. Le Guennec, and S. Briault. 2006.

Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation. The American journal of psychiatry

Lacoste, C., V. Barthaux, C. Iborra, M. Seagar, and M. Erard-Garcia. 2006.

MAU-8 is a Phosducin-like Protein required for G protein signaling in C. elegans. Developmental biology

Weston-Davies, W., I. Couillin, S. Schnyder, B. Schnyder, R. Moser, O. Lissina, G. C. Paesen, P. Nuttall, and B. Ryffel. 2005.

Arthropod-derived protein EV131 inhibits histamine action and allergic asthma. Ann N Y Acad Sci

Weber, M. A., S. Schnyder-Candrian, B. Schnyder, V. Quesniaux, V. Poli, C. L. Stewart, and B. Ryffel. 2005.

Endogenous leukemia inhibitory factor attenuates endotoxin response. Lab Invest

Ryffel, B., C. Fremond, M. Jacobs, S. Parida, T. Botha, B. Schnyder, and V. Quesniaux. 2005.

Innate immunity to mycobacterial infection in mice: critical role for toll-like receptors. Tuberculosis (Edinb)

Quesniaux, V., and B. Ryffel. 2005.

[Fatal tuberculosis despite adaptive immune response in the absence of MyD88]. Med Sci (Paris)

Noulin, N., V. F. Quesniaux, S. Schnyder-Candrian, B. Schnyder, I. Maillet, T. Robert, B. B. Vargaftig, B. Ryffel, and I. Couillin. 2005.

Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin. J Immunol

Laumonnier, F., S. Holbert, N. Ronce, F. Faravelli, S. Lenzner, C. E. Schwartz, J. Lespinasse, H. Van Esch, D. Lacombe, C. Goizet, F. Phan-Dinh Tuy, H. van Bokhoven, J. P. Fryns, J. Chelly, H. H. Ropers, C. Moraine, B. C. Hamel, and S. Briault. 2005.

Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate. Journal of medical genetics

Fremond, C., N. Allie, I. Dambuza, S. I. Grivennikov, V. Yeremeev, V. F. Quesniaux, M. Jacobs, and B. Ryffel. 2005.

Membrane TNF confers protection to acute mycobacterial infection. Respir Res

Brown, N., M. Jacobs, S. K. Parida, T. Botha, A. Santos, L. Fick, B. Gicquel, M. Jackson, V. Quesniaux, and B. Ryffel. 2005.

Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection. Infect Immun

Quesniaux, V. J., D. M. Nicolle, D. Torres, L. Kremer, Y. Guérardel, J. Nigou, G. Puzo, F. Erard, and B. Ryffel. 2004.

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans. J Immunol

Quesniaux, V., C. Fremond, M. Jacobs, S. Parida, D. Nicolle, V. Yeremeev, F. Bihl, F. Erard, T. Botha, M. Drennan, M. N. Soler, M. Le Bert, B. Schnyder, and B. Ryffel. 2004.

Toll-like receptor pathways in the immune responses to mycobacteria. Microbes Infect

Nicolle, D. M., X. Pichon, A. Bouchot, I. Maillet, F. Erard, S. Akira, B. Ryffel, and V. F. Quesniaux. 2004.

Chronic pneumonia despite adaptive immune response to Mycobacterium bovis BCG in MyD88-deficient mice. Lab Invest

Nicolle, D., C. Fremond, X. Pichon, A. Bouchot, I. Maillet, B. Ryffel, and V. J. Quesniaux. 2004.

Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice. Infect Immun

Laumonnier, F., F. Bonnet-Brilhault, M. Gomot, R. Blanc, A. David, M. P. Moizard, M. Raynaud, N. Ronce, E. Lemonnier, P. Calvas, B. Laudier, J. Chelly, J. P. Fryns, H. H. Ropers, B. C. Hamel, C. Andres, C. Barthélémy, C. Moraine, and S. Briault. 2004.

X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family. American journal of human genetics

Fremond, C. M., V. Yeremeev, D. M. Nicolle, M. Jacobs, V. F. Quesniaux, and B. Ryffel. 2004.

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. J Clin Invest

Drennan, M. B., D. Nicolle, V. J. Quesniaux, M. Jacobs, N. Allie, J. Mpagi, C. Frémond, H. Wagner, C. Kirschning, and B. Ryffel. 2004.

Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. Am J Pathol

Couillin, I., I. Maillet, B. B. Vargaftig, M. Jacobs, G. C. Paesen, P. A. Nuttall, J. Lefort, R. Moser, W. Weston-Davies, and B. Ryffel. 2004.

Arthropod-derived histamine-binding protein prevents murine allergic asthma. J Immunol

Raynaud, M., S. Dessay, N. Ronce, J. Opitz, M. Pembrey, C. Romano, C. Moraine, and S. Briault. 2003.

Skewed X chromosome inactivation in carriers is not a constant finding in FG syndrome. European journal of human genetics : EJHG

Heumann, D., R. Lauener, and B. Ryffel. 2003.

The dual role of LBP and CD14 in response to Gram-negative bacteria or Gram-negative compounds. J Endotoxin Res

Gumede, B., P. Folb, and B. Ryffel. 2003.

Oral artesunate prevents Plasmodium berghei Anka infection in mice. Parasitol Int

Fremond, C. M., D. M. Nicolle, D. S. Torres, and V. F. Quesniaux. 2003.

Control of Mycobacterium bovis BCG infection with increased inflammation in TLR4-deficient mice. Microbes Infect

Botha, T., and B. Ryffel. 2003.

Reactivation of latent tuberculosis infection in TNF-deficient mice. J Immunol

Schuurman, H. J., K. Menninger, M. Audet, A. Kunkler, C. Maurer, C. Vedrine, M. Bernhard, L. Gaschen, V. Brinkmann, and V. Quesniaux. 2002.

Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD. Transplantation

Laumonnier, F., N. Ronce, B. C. Hamel, P. Thomas, J. Lespinasse, M. Raynaud, C. Paringaux, H. Van Bokhoven, V. Kalscheuer, J. P. Fryns, J. Chelly, C. Moraine, and S. Briault. 2002.

Transcription factor SOX3 is involved in X-linked mental retardation with growth hormone deficiency. American journal of human genetics

Jacobs, M., L. Fick, N. Allie, N. Brown, and B. Ryffel. 2002.

Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice. Clin Chem Lab Med

Dessay, S., M. P. Moizard, J. L. Gilardi, J. M. Opitz, H. Middleton-Price, M. Pembrey, C. Moraine, and S. Briault. 2002.

FG syndrome: linkage analysis in two families supporting a new gene localization at Xp22.3 [FGS3]. American journal of medical genetics

Botha, T., and B. Ryffel. 2002.

Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model. Immunology

Abel, B., N. Thieblemont, V. J. Quesniaux, N. Brown, J. Mpagi, K. Miyake, F. Bihl, and B. Ryffel. 2002.

Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol

Núñez, M. T., A. Osorio, V. Tapia, A. Vergara, and C. V. Mura. 2001.

Iron-induced oxidative stress up-regulates calreticulin levels in intestinal epithelial (Caco-2) cells. Journal of cellular biochemistry

Nicolas, L. B., W. Pinoteau, S. Papot, S. Routier, G. Guillaumet, and S. Mortaud. 2001.

Aggressive behavior induced by the steroid sulfatase inhibitor COUMATE and by DHEAS in CBA/H mice. Brain research

Moser, R., V. Quesniaux, and B. Ryffel. 2001.

Use of transgenic animals to investigate drug hypersensitivity. Toxicology