{"id":4427,"date":"2023-08-17T16:27:04","date_gmt":"2023-08-17T14:27:04","guid":{"rendered":"https:\/\/www.inem.cnrs.fr\/?page_id=4427"},"modified":"2023-08-18T11:49:45","modified_gmt":"2023-08-18T09:49:45","slug":"cv-riteau","status":"publish","type":"page","link":"https:\/\/www.inem.cnrs.fr\/index.php\/cv-riteau\/","title":{"rendered":"CV Riteau"},"content":{"rendered":"\t\t
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Nicolas Riteau CV <\/h2>
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PERSONAL STATEMENT<\/span><\/b><\/p>

<\/span><\/span>\u00a0<\/span>I have a PhD in immunology (2008-2011) obtained at the university of Orleans, France. In Isabelle Couillin’s team, I studied the role of endogenous danger signals and their capacity to induce sterile lung inflammation and fibrosis. I performed a five-year post-doctoral experience (2012-2017) at the National Institutes of Health in Alan Sher’s laboratory where I studied CD4+ T follicular helper cells. I was recruited as CNRS scientist in 2018 at the INEM laboratory (https:\/\/www.inem.cnrs.fr\/). My current focus is on STING signaling and lung fibrosis. I am participating in the creation of a CNRS International Research Laboratory (IRL) in the field of immunology that will be located on Ribeir\u00e3o Preto\/University of S\u00e3o Paulo campus under the direction of Jos\u00e9 Carlos Alves Filho.<\/span><\/p>

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\u00a0<\/span><\/b>EDUCATION<\/span><\/b><\/p>

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2008-2011<\/span>\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>\u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/span>Immunology and Molecular Embryology laboratory, UMR6218<\/span><\/p>

Ph.D.\u00a0 <\/span><\/b>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0CNRS and University of Orleans, France<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Co-Advisors: Dr. Isabelle Couillin and Pr. Bernhard Ryffel<\/span><\/p>

2006-2008\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/span><\/span>Genome and Proteome Expression and Regulation<\/span><\/p>

M.S.<\/span><\/b>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 University of Science, Orleans, France <\/span><\/p>

2003-2006\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span>Cellular Biology and Physiology Department of Chemistry<\/span><\/p>

B.S.<\/span><\/b>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 University of Science, Orleans, France\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/p>

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PROFESSIONAL Experience<\/span><\/b><\/p>

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2018(Oct)-present\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Scientist (CRCN, Charg\u00e9 de recherche de classe normale)<\/b>, Experimental and Molecular Immunology and Neurogenetics (INEM), UMR7355, CNRS, France<\/span><\/p>

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2017-2018(Sep)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Research Fellow<\/b>, Experimental and Molecular Immunology and Neurogenetics (INEM), UMR7355, CNRS, France<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Role of self-nucleic acids in sterile pulmonary inflammation<\/i><\/span><\/p>

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2012-2017(May)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Postdoctoral Fellow<\/b>, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Adjuvants in the development and function of T Follicular Helper cells <\/i><\/span><\/p>

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2011 (3 months)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Visiting Scientist<\/b>, Laboratory of Immuno-pharmacology headed by Pr. Mauro Martins Teixeira, Belo Horizonte, MG, Brazil<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Standardization of human PBMC cultures<\/i><\/span><\/p>

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2008-2011\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ph.D. Candidate<\/b>, Immunology and Molecular Embryology, UMR6218, CNRS, France<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Innate immunity and inflammasome: role of endogenous danger signals <\/i><\/span><\/p>

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2010 (2 months)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Agency for Science, Technology and Research (A*STAR), Singapore<\/span><\/p>

Study of dendritic cells depletion during lung inflammation and fibrosis induced by bleomycin<\/span><\/p>

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2007 (3 months)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Department of Medical Biotechnology, Jagiellonian University, Krakow, Poland<\/span><\/p>

Heme-oxygenase-1 (HO-1) human promoter regulation in response to different inducers<\/span><\/p>

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Summer 2006\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Pharmaceutical company SERVIER, Orleans, France<\/span><\/p>

The use of bactosomes in identification and contribution of liver P450 involved in drug metabolism<\/span><\/p>

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Fellowships and Awards<\/span><\/b><\/p>

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2021\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u201cBright Spark Award\u201d 6th European Congress of Immunology <\/span><\/p>

2019\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Selected to attend the InflamSchool, Ribeirao Preto, Brasil<\/span><\/p>

2019 (Oct)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Recipient of the \u201cC\u00c1TEDRAS FRANCO-BRASILEIRAS NA UFMG\u201d award to be hosted as a month visiting professor at the Universidade Federal de Minas Gerais (UFMG), Brasil<\/span><\/p>

2012-2017\u00a0\u00a0\u00a0\u00a0\u00a0 NIH Intramural Research Training Award (IRTA) Fellowship<\/span><\/p>

2017 (March)\u00a0 Scholarship to serve as a Conference Assistant at the Keystone Symposium – Type I Interferon: Friend and Foe Alike, Banff, Alberta, Canada <\/span><\/p>

2014\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Winner of the Fellows’ Award for Research Excellence (FARE), NIH<\/span><\/p>

2013\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Selected to attend the 3rd Network of Immunology Frontier Winter school of Advanced immunology, Osaka, Japan<\/span><\/p>

2008-2011\u00a0\u00a0\u00a0\u00a0\u00a0 MRT Grant, CNRS, France <\/span><\/p>

(<\/sup><\/span>1-20<\/span><\/sup><\/a><\/span>)<\/span><\/sup><\/span><\/p>

Publications<\/span><\/b><\/p>

<\/span>\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/p>

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As of August 2023. H-Index : 18<\/b> ; Sum of Times Cited: 2,3K Web of Science<\/b><\/span><\/p>

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1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>de Moura Rodrigues D, Lacerda-Queiroz N, Couillin I and Riteau N<\/b>. STING Targeting in Lung Diseases. Cells. 2022 Nov 3;11(21):3483. doi: 10.3390\/cells11213483<\/span><\/p>

2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Huot-Marchand S, Nascimento M, Culerier E, Bourenane M, Savigny F, Panek C, Serdjebi C, Le Bert M, Quesniaux VFJ, Ryffel B, Broz P, Riteau N<\/b>, Gombault A, Couillin I. Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3. Front Immunol. 2022 Aug 15;13:918507. doi: 10.3389\/fimmu.2022.918507.<\/span><\/p>

3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Couillin I. and Riteau N<\/b>. STING signaling and sterile inflammation Front Immunol. 2021 Oct 1;12:753789. doi: 10.3389\/fimmu.2021.753789.<\/span><\/p>

4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Savigny F., Schricke C., Lacerda-Queiroz N, Meda M., Nascimento M., Huot-Marchand S., Da Gama Monteiro F., Ryffel B., Gombault A., Le Bert M., Couillin I. and Riteau N<\/b>. Protective role of the nucleic acid sensor STING in pulmonary fibrosis. Front Immunol. 2021 Jan 8;11:588799<\/span><\/p>

5.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Nascimento M, Huot-Marchand S, Gombault A, Panek C, Bourinet M, Fanny M, Savigny F, Schneider P, Le Bert M, Ryffel B, Riteau N<\/b>, Quesniaux VFJ, Couillin I. B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.Front Immunol. 2020 Jul 29;11:1622.<\/span><\/p>

6.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N<\/span><\/b>., and Bernaudin, J. F. 2020 In addition to mTOR and JAK\/STAT, NLRP3 inflammasome is another key pathway activated in sarcoidosis.The European respiratory journal 55 10.1183<\/span><\/p>

7.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Nascimento, M., A. Gombault, N. Lacerda-Queiroz, C. Panek, F. Savigny, M. Sbeity, M. Bourinet, M. Le Bert, N. Riteau<\/b>, B. Ryffel, V. F. J. Quesniaux, and I. Couillin. 2019. Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice. Sci Rep 9: 14848.<\/span><\/p>

8.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Amaral, E. P., D. L. Costa, S. Namasivayam, N. Riteau<\/b>, O. Kamenyeva, L. Mittereder, K. D. Mayer-Barber, B. B. Andrade, and A. Sher. 2019. A major role for ferroptosis in Mycobacterium tuberculosis-induced cell death and tissue necrosis. J Exp Med 216: 556-570.<\/span><\/p>

9.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Fanny, M., M. Nascimento, L. Baron, C. Schricke, I. Maillet, M. Akbal, N. Riteau<\/b>, M. Le Bert, V. Quesniaux, B. Ryffel, A. Gombault, S. Meme, W. Meme, and I. Couillin. 2018. The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Front Immunol 9: 1476.<\/span><\/p>

10.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Fang, D., K. Cui, K. Mao, G. Hu, R. Li, M. Zheng, N. Riteau<\/b>, S. L. Reiner, A. Sher, K. Zhao, and J. Zhu. 2018. Transient T-bet expression functionally specifies a distinct T follicular helper subset. J Exp Med 215: 2705-2714.<\/span><\/p>

11.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Amaral, E. P., N. Riteau<\/b>, M. Moayeri, N. Maier, K. D. Mayer-Barber, R. M. Pereira, S. L. Lage, A. Kubler, W. R. Bishai, M. R. D’Imperio-Lima, A. Sher, and B. B. Andrade. 2018. Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages. Front Immunol 9: 1427<\/span><\/p>

12.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N<\/span><\/b>.*, Radtke, A. J*., Anderson, C. F*., Rausch, K., Scaria, P., Kelnhofer, E. R., Howard, R. F., Sher, A., Germain, R. N., and Duffy, P. (2017) Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate. Sci Rep 7, 40312<\/span><\/p>

13.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Lacerda-Queiroz, N., Riteau<\/b>, N., Eastman, R. T., Bock, K. W., Orandle, M. S., Moore, I. N., Sher, A., Long, C. A., Jankovic, D., and Su, X. Z. (2017) Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model. Sci Rep 7, 10438<\/span><\/p>

14.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N<\/span><\/b>., and Sher, A. (2016) Chitosan: An Adjuvant with an Unanticipated STING. Immunity 44, 522-524<\/span><\/p>

15.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N., Radtke, A. J., Shenderov, K., Mittereder, L., Oland, S. D., Hieny, S., Jankovic, D., and Sher, A. (2016) Water-in-Oil-Only Adjuvants Selectively Promote T Follicular Helper Cell Polarization through a Type I IFN and IL-6-Dependent Pathway. Journal of immunology 197, 3884-3893<\/span><\/p>

16.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N<\/span><\/b>., Gombault, A., and Couillin, I. (2016) Assessment of Inflammasome Activation by Cytokine and Danger Signal Detection. Methods Mol Biol 1417, 63-74<\/span><\/p>

17.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Charmoy, M., Hurrell, B. P., Romano, A., Lee, S. H., Ribeiro-Gomes, F., Riteau, N.<\/b>, Mayer-Barber, K., Tacchini-Cottier, F., and Sacks, D. L. (2016) The Nlrp3 inflammasome, IL-1beta, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL\/6 mice. Eur J Immunol 46, 897-911<\/span><\/p>

18.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Baron, L., Gombault, A., Fanny, M., Villeret, B., Savigny, F., Guillou, N., Panek, C., Le Bert, M., Lagente, V., Rassendren, F., Riteau, N.<\/b>, and Couillin, I. (2015) The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Cell death & disease 6, e1629<\/span><\/p>

19.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Andrade, B. B., Pavan Kumar, N., Amaral, E. P., Riteau, N.<\/b>, Mayer-Barber, K. D., Tosh, K. W., Maier, N., Conceicao, E. L., Kubler, A., Sridhar, R., Banurekha, V. V., Jawahar, M. S., Barbosa, T., Manganiello, V. C., Moss, J., Fontana, J. R., Marciano, B. E., Sampaio, E. P., Olivier, K. N., Holland, S. M., Jackson, S. H., Moayeri, M., Leppla, S., Sereti, I., Barber, D. L., Nutman, T. B., Babu, S., and Sher, A. (2015) Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis. Journal of immunology 195, 2763-2773<\/span><\/p>

20.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N.*<\/span><\/b>, Shenderov, K.*, Yip, R., Mayer-Barber, K. D., Oland, S., Hieny, S., Fitzgerald, P., Oberst, A., Dillon, C. P., Green, D. R., Cerundolo, V., and Sher, A. (2014) Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1beta in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway. Journal of immunology 192, 2029-2033<\/span><\/p>

21.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Cardone, M., Dzutsev, A. K., Li, H., Riteau, N<\/b>., Gerosa, F., Shenderov, K., Winkler-Pickett, R., Provezza, L., Riboldi, E., Leighty, R. M., Orr, S. J., Steinhagen, F., Wewers, M. D., Sher, A., Anderson, S. K., Goldszmid, R., McVicar, D. W., Lyakh, L., and Trinchieri, G. (2014) Interleukin-1 and interferon-gamma orchestrate beta-glucan-activated human dendritic cell programming via IkappaB-zeta modulation. PloS one 9, e114516<\/span><\/p>

22.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N.<\/span><\/b>*, Baron, L.*, Villeret, B., Guillou, N., Savigny, F., Ryffel, B., Rassendren, F., Le Bert, M., Gombault, A., and Couillin, I. (2012) ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell death & disease 3, e403<\/span><\/p>

23.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Gasse, P., Riteau, N.<\/b>, Vacher, R., Michel, M. L., Fautrel, A., di Padova, F., Fick, L., Charron, S., Lagente, V., Eberl, G., Le Bert, M., Quesniaux, V. F., Huaux, F., Leite-de-Moraes, M., Ryffel, B., and Couillin, I. (2011) IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis. PloS one 6, e23185<\/span><\/p>

24.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Conforti-Andreoni, C., Spreafico, R., Qian, H. L., Riteau, N.<\/b>, Ryffel, B., Ricciardi-Castagnoli, P., and Mortellaro, A. (2011) Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18. Journal of immunology 187, 5842-5850<\/span><\/p>

25.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Yazdi AS, Guarda G, Riteau N<\/b>, Drexler SK, Tardivel A, Couillin I, Tschopp J. Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 19449-19454 <\/span><\/p>

26.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N.<\/span><\/b>, Gasse, P., Fauconnier, L., Gombault, A., Couegnat, M., Fick, L., Kanellopoulos, J., Quesniaux, V. F., Marchand-Adam, S., Crestani, B., Ryffel, B., and Couillin, I. (2010) Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. American journal of respiratory and critical care medicine 182, 774-783<\/span><\/p>

27.\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/b>Riteau, N.*<\/span><\/b>, Gasse, P.* , Charron, S., Girre, S., Fick, L., Petrilli, V., Tschopp, J., Lagente, V., Quesniaux, V. F., Ryffel, B., and Couillin, I. (2009) Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. American journal of respiratory and critical care medicine 179, 903-913<\/span><\/p>

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*: Equal contribution<\/b><\/span><\/p>

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Meetings and Presentations<\/span><\/b><\/p>

<\/p>
\u00a0<\/td><\/tr>
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2023\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Journ\u00e9es d\u2019Animation Scientifique, F\u00e9RI<\/b> (F\u00e9d\u00e9ration de recherche en infectiologie), Tours, France. Oral Presentation, \u201cChronic ozone induces lung inflammation through<\/p>

NLRP6-dependent activation of pyroptosis and necroptosis\u201d<\/p>

\u00a0<\/p>

2023\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Inflamma VIII<\/b>, Centro de Conven\u00e7\u00f5es do Hospital S\u00edrio Liban\u00eas, S\u00e3o Paulo, Brazil<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>Invited speaker, \u201cProtective role of STING in pulmonary fibrosis\u201d<\/span><\/p>

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2022\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Alan Sher Symposium, <\/b>Lipsett Auditorium, NIH, Bethesda, USA<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Oral Presentation, \u201cProtective role of STING in pulmonary fibrosis\u201d<\/span><\/p>

\u00a0<\/span><\/p>

2021\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 European Congress of Immunology (ECI)<\/b> Oral Presentation (remote) \u201cProtective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis\u201d<\/span><\/p>

\u00a0<\/span><\/p>

2019 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 LE STUDIUM WORKSHOP<\/b>: DNA sensing and STING activation in lung inflammation, Orl\u00e9ans, France<\/span><\/p>

Oral Presentation, \u201cProtective role of the STING signaling pathway in pulmonary fibrosis\u201d<\/span><\/p>

\u00a0<\/span><\/p>

2019 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 GREMI Meeting<\/b>: <\/b>Inflamed Cells: Latest News From Inside – Pasteur Institute, Paris, France<\/span><\/p>

Poster Presentation, \u201cSTING signaling pathway regulates idiopathic pulmonary fibrosis\u201d<\/span><\/p>

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2018 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 XLIII Congress of the Brazilian society of immunology<\/b>, Ouro Preto, MG, Brazil<\/span><\/p>

Poster Presentation, \u201cProtective role of the nucleic acid sensor STING signaling pathway in idiopathic pulmonary fibrosis\u201d<\/span><\/p>

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2018 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Journ\u00e9es d\u2019Animation Scientifique, F\u00e9RI<\/b> (F\u00e9d\u00e9ration de recherche en infectiologie), Tours, France<\/b><\/p>

Oral Presentation, \u201cProtective role of the STING signaling pathway in pulmonary fibrosis\u201d<\/span><\/p>

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2017 \u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Journ\u00e9e de la Recherche Respiratoire<\/b> (J2R<\/b>), Quebec, Canada<\/p>

Poster Presentation, \u201cRole of self-nucleic acids as danger signals activating type I\/III interferon signaling pathways in cigarette smoke-induced neutrophilic inflammation\u201d<\/span><\/p>

\u00a0<\/span><\/p>

2017 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Keystone Symposium<\/b>: Type I Interferon: Friend and Foe Alike, Banff, Alberta, Canada Opposing roles of type I interferon in the promotion of T follicular -helper versus -regulatory cells by water-in-oil only adjuvants\u201d <\/span><\/p>

\u00a0<\/span><\/p>

2016\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Immunology Interest group<\/b>, Washington, USA<\/span><\/p>

Oral Presentation, \u201cWater-in-oil only adjuvants selectively promote Tfh polarization through a type I interferon and IL-6 dependent pathway\u201d<\/span><\/p>

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2016\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Keystone Symposium: <\/b>T Follicular Helper Cells and Germinal Centers, Monterey, CA, USA<\/span><\/p>

Oral Presentation, \u201cDual roles for Myd88 and type I IFN in adjuvant induced Tfh polarization\u201d<\/span><\/p>

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2015\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 12th<\/sup> World Congress on Inflammation<\/b>, Boston, MA, USA<\/span><\/p>

Poster Presentation, \u201cDeciphering the signals required for follicular helper T cell generation in the absence of exogenous microbial stimuli\u201d<\/span><\/p>

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2015\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Immunology Interest group<\/b>, Washington, USA<\/span><\/p>

Poster Presentation, \u201cDeciphering the signals required for follicular helper T cell generation in the absence of exogenous microbial stimuli\u201d<\/span><\/p>

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2013\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Research Festival<\/b>, National Institutes of Health, Bethesda, MD, USA<\/span><\/p>

Oral Presentation, \u201cER stress licenses macrophages to produce mature IL-1\u03b2 in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway\u201d<\/span><\/p>

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2013\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Immunology Interest group<\/b>, Washington, USA<\/span><\/p>

Oral Presentation, \u201cER stress licenses macrophages to produce mature IL-1\u03b2 in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway\u201d<\/span><\/p>

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2011\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 10th World Congress of Inflammation<\/b>, Paris, France <\/span><\/p>

Oral Presentation, \u201cPurinergic Signaling: a common pathway for crystals-mediated inflammasome activation\u201d<\/span><\/p>

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2010\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 British Thoracic Society Winter Meeting<\/b>, London, UK<\/span><\/p>

Oral Presentation, \u201cNanoparticles cause pulmonary inflammation through IL-1<\/span>a<\/span> and partial activation of the NLRP3 inflammasome\u201d <\/span><\/p>

\u00a0<\/span><\/p>

2010\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 13th International Conference on Lymphocyte Activation and Immune Regulation<\/b>. Newport Beach, CA, USA <\/span><\/p>

Poster Presentation, \u201cExtracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis <\/span><\/p>

\u00a0<\/span><\/p>

2009\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 European Congress of Immunology<\/b> (ECI), Berlin, Germany <\/span><\/p>

Poster Presentation, \u201cUric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis\u201d<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/p>

2008\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Journ\u00e9e de la Recherche Respiratoire<\/b> (J2R), Paris, France<\/p>

Poster Presentation, \u201cUric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis\u201d<\/span><\/p>

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Committee<\/span><\/b><\/p>

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2023-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Member of CED65 <\/b>\u00ab\u00a0Coll\u00e8ge des \u00e9coles doctorales et HDR\u00a0\u00bb, University of Orl\u00e9ans<\/p>

2022-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Board Member of the GREMI <\/b>(\u00ab\u00a0<\/b>Recherche sur les m\u00e9diateurs de l’inflammation\u00a0\u00bb)<\/p>

2016 – \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Review Editor in Frontiers in Immunology<\/span><\/p>

2013 – 2016\u00a0\u00a0\u00a0\u00a0 Assistant Editor, Inflammasome, Versita<\/span><\/p>

2013 – 2016\u00a0\u00a0\u00a0\u00a0 Laboratory of Parasitic diseases post-doc committee member, NIH, USA<\/span><\/p>

2008 – 2011\u00a0\u00a0\u00a0\u00a0 Science University Delegate, University of Orleans Advisory Committee<\/span><\/p>

\u00a0<\/span><\/p>

\u00a0<\/span><\/b><\/p>

reviewing ACTIVITIES<\/span><\/b><\/p><\/div>

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2012-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Reviewer for PLOS-ONE<\/b> and JOVE<\/b> <\/span><\/p>

2014-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Reviewer for The Journal of Immunology<\/b> and Respiratory Research<\/b><\/span><\/p>

2016-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Reviewer for Trends in Immunology<\/b><\/span><\/p>

2016- \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Reviewer for Frontiers in Immunology<\/b><\/span><\/p>

2018-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/b>Reviewer for Mediators of inflammation<\/b><\/span><\/p>

2019- \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/b>Reviewer for European Respiratory Journal<\/b>, International Journal of Molecular Sciences<\/b>, Pharmaceutics<\/b>, Prostaglandins and other lipid mediators<\/b><\/span><\/p>

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Teaching and Mentoring Experience<\/span><\/b><\/p>

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2020\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 HDR<\/b> (\u201chabilitation \u00e0 diriger des recherches\u201d) delivered by the University of Orl\u00e9ans<\/span><\/p>

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2017-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0PhD Director<\/b> (2021-2024)<\/span><\/p>

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 PhD Co-director<\/b> (2022-2023) Cotutelle EIFFEL <\/span><\/p>

BTS and master 1\/2 students<\/span><\/p>

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2008-2011\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Teaching assistant \u201cmoniteur<\/b>\u201d. Practical courses to Undergraduate Students in Physiology (96 hours\/year) and Immunology lectures to B.Sc students, Science University, Orleans, France<\/span><\/p>

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2008-2011 \u00a0\u00a0\u00a0\u00a0\u00a0 One second year BTS, one Master 2 and one PhD students, Immunologie et Embryologie mol\u00e9culaire, UMR6218, CNRS and University of Orleans, France<\/span><\/p>

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Languages<\/span><\/b><\/p>

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French: Mother tongue\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/p>

English: Read, written, spoken<\/span><\/p>

Brazilian Portuguese: Read, written, spoken<\/p>

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\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Retour au site du laboratoire Nicolas Riteau CV Updated Aug 2023 PERSONAL STATEMENT \u00a0I have a PhD in immunology (2008-2011) obtained at the university of Orleans, France. In Isabelle Couillin’s team, I studied the role of endogenous danger signals and their capacity to induce sterile lung inflammation and fibrosis. I performed a five-year post-doctoral experience…
Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-4427","page","type-page","status-publish","hentry"],"yoast_head":"\nINEM CV Riteau -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.inem.cnrs.fr\/index.php\/cv-riteau\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"INEM CV Riteau -\" \/>\n<meta property=\"og:description\" content=\"Retour au site du laboratoire Nicolas Riteau CV Updated Aug 2023 PERSONAL STATEMENT \u00a0I have a PhD in immunology (2008-2011) obtained at the university of Orleans, France. 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