{"id":44,"date":"2021-07-22T10:59:23","date_gmt":"2021-07-22T08:59:23","guid":{"rendered":"https:\/\/www.inem.cnrs.fr\/?page_id=44"},"modified":"2024-10-22T15:49:41","modified_gmt":"2024-10-22T13:49:41","slug":"groupe-inflammation-signaux-de-danger-infection-et-pathologies-pulmonaires-projets","status":"publish","type":"page","link":"https:\/\/www.inem.cnrs.fr\/index.php\/groupe-inflammation-signaux-de-danger-infection-et-pathologies-pulmonaires-projets\/","title":{"rendered":"Groupe Inflammation, signaux de danger, infection et pathologies pulmonaires-Projets"},"content":{"rendered":"\t\t
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RETOUR AUX EQUIPES<\/a><\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Groupe Inflammation, signaux de danger, infection et pathologies pulmonaires  <\/span><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Projets en cours<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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European funding in Region Centre-Val de Loire (FEDER N\u00b02024-00012066) Exposome & Inflammation: D\u00e9veloppement et transfert de mod\u00e8les d\u2019\u00e9tude pr\u00e9clinique et acquisition de connaissance.<\/strong><\/p>

1) Exposition aux polluants a\u00e9riens et allerg\u00e8nes; 2) Exposition aux intrants m\u00e9dicamenteux ou pesticides; 3) Interactions crois\u00e9es exposome – microbiote et ses d\u00e9riv\u00e9s – r\u00e9ponse de l\u2019h\u00f4te.<\/p>

Coordinateur:\u00a0<\/span>Val\u00e9rie Quesniaux\u00a0<\/span><\/p>

Financement: FEDER en r\u00e9gion Centre Val de Loire: cofinanc\u00e9 par l’union Europ\u00e9enne\u00a0<\/strong><\/p>

P\u00e9riode: 2021-2027<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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R\u00f4le du r\u00e9cepteur NLRP6 dans l\u2019inflammation pulmonaire en r\u00e9ponse la fum\u00e9e de cigarette et l\u2019exacerbation de la BPCO suite aux infections bact\u00e9riennes <\/strong><\/p>

Coordinateur: Isabelle Couillin<\/p>

Financement: Agence Nationale pour la Recherche ANR AAPG 2019<\/strong> Smoke6<\/p>

P\u00e9riode: 2019-2024<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Projets clotur\u00e9s<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Self-ADN et<\/strong> activation de la voie cGAS-STING en pathologie pulmonaire inflammatoire<\/strong><\/p>

Coordinateur: Val\u00e9rie Quesniaux<\/p>

Financement: Fondation pour la Recherche M\u00e9dicale<\/strong><\/p>

P\u00e9riode: 2021-2023<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Associer les \u00e9quipes de la F\u00e9d\u00e9ration de Recherche en Infectiologie F\u00e9RI<\/strong> travaillant sur la grippe (humaine et aviaire), la TB (humaine et bovine), l\u2019inflammation pulmonaire en r\u00e9ponse aux polluants et le d\u00e9veloppement de petites mol\u00e9cules dans un projet de recherche en ligne avec le concept \u2018One Health\u2019 dans le domaine des \u2018Host-Directed Therapies\u2019 (HDT).<\/p>

Coordinateur: Val\u00e9rie Quesniaux<\/p>

Financement: European funding in Region Centre-Val de Loire<\/strong> (FEDER N\u00b0 EX010381). EURO-F\u00e9ri<\/p>

P\u00e9riode: 2020-2023<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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D\u00e9veloppement et transfert de mod\u00e8les pr\u00e9cliniques murins pour la recherche de cibles th\u00e9rapeutiques et la caract\u00e9risation de nouveaux m\u00e9dicaments \u2013 Neuroinflammation, Inflammation pulmonaire et Infection<\/strong><\/p>

Coordinateur: Val\u00e9rie Quesniaux<\/p>

Financement: European funding in Region Centre-Val de Loire<\/strong> (FEDER N\u00b0 EX005756)<\/p>

P\u00e9riode: 2019-2022<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Prot\u00e9olyse et Interleukine-1\u03b2 Associ\u00e9es aux Inflammations Pulmonaires Neutrophiliques (PIRANA)<\/strong><\/p>

Coordinateur: Brice KORKMAZ<\/p>

Financement: R\u00e9gion Centre-Val de Loire<\/strong> \u2013 Appels \u00e0 projets \u00ab Recherche d\u2019initiative acad\u00e9mique \u00bb<\/p>

P\u00e9riode: 2020-2021<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00a0<\/p>

Biotarget Phase 1<\/b> (2015-2017) Partner
D\u00e9veloppement et transfert de mod\u00e8les pr\u00e9cliniques murins<\/p>

ARD2020 Bio-Model <\/b>(2017\/2019) Partner<\/p>

International Exchanges <\/b>(2018-2020) Partner
Acethylcholine and Th2 pulmonary immunity<\/p>

F\u00e9d\u00e9ration de recherch\u00e9 en infectiologie (FeRI)<\/b> (2018) Partner
Lung Infection and Inflammation: a role for neutrophilic inflammasomes<\/p>

Appel \u00e0 projet r\u00e9gion centre d\u2019int\u00e9r\u00eat r\u00e9gional (APR-IR)<\/b> (2018-2019) Partner
Etude et utilisation \u00e0 vis\u00e9e th\u00e9rapeutique de l’interleukine-7 dans l’inflammation pulmonaire \u00bb (7UP)<\/p>

Conseil G\u00e9n\u00e9ral du Loiret<\/b> (2015-2017) Coordinateur I Couillin
Fum\u00e9e de cigarette et inflammation pulmonaire: r\u00f4le de l\u2019inflammasome NLRP6 (Inflamm6)<\/p>

Ligue Contre le Cancer <\/b>(2015-2017) Partner
R\u00e9cepteurs P2X7 et d\u00e9veloppement m\u00e9tastatique dans le cancer du sein<\/p>

R\u00e9gion Centre <\/b>(2013-2015) Partner
Modulation des r\u00e9cepteurs P2X7 par les acides gras n-3 dans le cancer et l’inflammation (CancerInflam N3)<\/p>

Association pour la Recherche sur les Nicotian\u00e9es (ARN) <\/b>(2012-2013).
Coordinateur Isabelle Couillin
Role of the Nlrp2 and Nlrp6 inflammasomes in pulmonary inflammation and epithelial self-renewal upon lung injury induced by airway exposure to cigarette smoke<\/p>

Recherche Sant\u00e9 Respiratoire (RSR)<\/b> (2011- 2012) Coordinateur Isabelle Couillin
M\u00e9canismes de l\u2019inflammation pulmonaire aux nanoparticules de m\u00e9taux: r\u00f4le de l\u2019inflammasome et de la signalisation purinergique<\/p>

Agence nationale de la recherche (ANR) MI2<\/b> (2011- 2013) Coordinateur: Isabelle Couillin
Purinergic receptors signaling: toward the identification of therapeutic targets in inflammatory lung disease (PurPID)<\/p>

\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

RETOUR AUX EQUIPES Pr\u00e9sentation Membres Projets Publications Groupe Inflammation, signaux de danger, infection et pathologies pulmonaires   Projets en cours European funding in Region Centre-Val de Loire (FEDER N\u00b02024-00012066) Exposome & Inflammation: D\u00e9veloppement et transfert de mod\u00e8les d\u2019\u00e9tude pr\u00e9clinique et acquisition de connaissance. 1) Exposition aux polluants a\u00e9riens et allerg\u00e8nes; 2) Exposition aux intrants m\u00e9dicamenteux ou…
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